Article
RAS and Hedgehog--partners in crime.
Frontiers in bioscience (Landmark edition) - 1 Jun 2011
Lauth Matthias
Abstract excerpt
Both RAS and Hedgehog (HH) pathway activation can be found in approximately one third of all cancers. In many cases, this activation occurs in the same tumor types, suggesting a positive impact of a simultaneous activation of RAS and HH on tumor development. This review aims to summarize the curr...
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