Article
ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans.
Journal of cell science - 1 Feb 2013
Sengupta Madhu S, Low Wai Yee, Patterson Joseph R, Kim Hyun-Min, Traven Ana, Beilharz Traude H, Colaiácovo Monica P, Schisa Jennifer A, Boag Peter R
Abstract excerpt
Large cytoplasmic ribonucleoprotein germ granule complexes are a common feature in germ cells. In C. elegans these are called P granules and for much of the life-cycle they associate with nuclear pore complexes in germ cells. P granules are rich in proteins that function in diverse RNA pathways. Here we report that the C. elegans homolog of the eIF4E-transporter IFET-1 is required for oogenesis but not...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
