Article
Role of p54 RNA helicase activity and its C-terminal domain in translational repression, P-body localization and assembly.
Molecular biology of the cell - 1 May 2009
Minshall Nicola, Kress Michel, Weil Dominique, Standart Nancy
Abstract excerpt
The RNA helicase p54 (DDX6, Dhh1, Me31B, Cgh-1, RCK) is a prototypic component of P-(rocessing) bodies in cells ranging from yeast to human. Previously, we have shown that it is also a component of the large cytoplasmic polyadenylation element-binding protein translation repressor complex in Xenopus oocytes and that when tethered to the 3' untranslated region, Xp54 represses reporter mRNA translation. Here, we...
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