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Article

Cap binding-independent recruitment of eIF4E to cytoplasmic foci.

Biochimica et biophysica acta - 1 Jul 2012

Ferrero Paola V, Layana Carla, Paulucci Ezequiel, Gutiérrez Pablo, Hernández Greco, Rivera-Pomar Rolando V

Abstract excerpt

Eukaryotic translation initiation factor 4E (eIF4E) is required for cap-dependent initiation. In addition, eIF4E occurs in cytoplasmic foci such as processing bodies (PB) and stress granules (SG). We examined the role of key functional amino acid residues of eIF4E in the recruitment of this protein to cytoplasmic foci. We demonstrate that tryptophan residues required for mRNA cap recognition are not required for...

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Identifiers

PMID: 22507384
DOI: 10.1016/j.bbamcr.2012.03.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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