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Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) during <i>Caenorhabditis elegans</i> oogenesis

11 Aug 2008

Abstract excerpt

During oogenesis, numerous messenger RNAs (mRNAs) are maintained in a translationally silenced state. In eukaryotic cells, various translation inhibition and mRNA degradation mechanisms congregate in cytoplasmic processing bodies (P bodies). The P body protein Dhh1 inhibits translation and promotes decapping-mediated mRNA decay together with Pat1 in yeast, and has been implicated in mRNA storage in metazoan...

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PMID: 18695045
DOI: 10.1083/jcb.200801183

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