Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biochemistry of growth inhibition by ammonium ions in mammalian cells

20 Jun 1994

Abstract excerpt

The intracellular pool of UDP-N-acetylglucosamine and UDP-N-acetylgalactosamine has been shown to act as a central target during the inhibitory action of ammonium ions in vitro cultivated mammalian cell cultures. This pool has been demonstrated to be elevated at the end of a batch cultivation and very quickly as a response to exogenously applied ammonium chloride by using four different cell lines (hybridoma,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Pancreatic function and diabetes
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18618684
DOI: 10.1002/bit.260440207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Biochemistry of growth inhibition by ammonium ions in mammalian cellsPMID 18618684Read ↗

Amino acid and glucose metabolism in fed‐batch CHO cell culture affects antibody production and glycosylationSemantic proximity Read ↗

Ammonium Induces Aberrant Blastocyst Differentiation, Metabolism, pH Regulation, Gene Expression and Subsequently Alters Fetal Development in the MouseSemantic proximity Read ↗

The concentrations of glutamine and ammonia in commercially available cell culture mediaSemantic proximity Read ↗

Mutation-induced metabolite pool alterations in Corynebacterium glutamicum: towards the identification of nitrogen control signals.Semantic proximity Read ↗

The enhancement of antibody concentration and achievement of high cell density CHO cell cultivation by adding nucleosideSemantic proximity Read ↗

Allosteric Activation of Escherichia coli Glucosamine-6-Phosphate Deaminase (NagB) In Vivo Justified by Intracellular Amino Sugar Metabolite Concentrations.Semantic proximity Read ↗

A multi‐pronged investigation into the effect of glucose starvation and culture duration on fed‐batch CHO cell cultureSemantic proximity Read ↗

Characterization of metabolic responses, genetic variations, and microsatellite instability in ammonia-stressed CHO cells grown in fed-batch cultures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.