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Article

The proper connection between shelterin components is required for telomeric heterochromatin assembly.

Genes & development - 1 Apr 2016

Wang Jiyong, Cohen Allison L, Letian Anudari, Tadeo Xavier, Moresco James J, Liu Jinqiang, Yates John R, Qiao Feng, Jia Songtao

Abstract excerpt

Telomeric regions contain prominent sites of heterochromatin, which is associated with unique histone modification profiles such as the methylation of histone H3 at Lys9 (H3K9me). In fission yeast, the conserved telomeric shelterin complex recruits the histone H3K9 methyltransferase complex CLRC to establish subtelomeric heterochromatin. Although many shelterin mutations affect subtelomeric heterochromatin...

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Share to Chromatin Assembly and Disassembly
Share to Heterochromatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone-Lysine N-Methyltransferase

Share to Histone Methyltransferases

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

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Source

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Identifiers

PMID: 26988418
DOI: 10.1101/gad.266718.115
PMCID: PMC4826398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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