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Article

Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer.

Nucleic acids research - 1 Sept 2003

Kibe Tatsuya, Tomita Kazunori, Matsuura Akira, Izawa Daisuke, Kodaira Tsutomu, Ushimaru Takashi, Uritani Masahiro, Ueno Masaru

Abstract excerpt

The Schizosaccharomyces pombe Ku70-Ku80 heterodimer is required for telomere length regulation. Lack of pku70+ results in telomere shortening and striking rearrangements of telomere-associated sequences. We found that the rearrangements of telomere-associated sequences in pku80+ mutants are Rhp51 dependent, but not Rad50 dependent. Rhp51 bound to telomere ends when the Ku heterodimer was not present at telomere...

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Identifiers

PMID: 12930956
DOI: 10.1093/nar/gkg718
PMCID: PMC212814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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