Article
Minority report: hidden memory genomes in HIV-1 quasispecies and possible clinical implications.
AIDS reviews - 1 Jan 2000
Briones Carlos, Domingo Esteban
Abstract excerpt
The RNA viruses replicate as complex distributions of closely related genomes termed viral quasispecies. The behavior of the evolving quasispecies and its response to selective pressures such as antiviral treatment is influenced by the ensemble of mutants that compose the viral population. One such influence is the presence of minority subpopulations in the mutant spectra of viral quasispecies. Biologically...
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