Article
Synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies.
Journal of molecular biology - 24 Oct 2003
Ruiz-Jarabo Carmen M, Miller Eric, Gómez-Mariano Gema, Domingo Esteban
Abstract excerpt
Viral quasispecies are endowed with a memory of their past evolutionary history in the form of minority genomes of their mutant spectra. To determine the fate of memory genomes in evolving viral quasispecies, we have measured memory levels of antigenic variant of foot-and-mouth disease virus (FMDV) RED, which includes an Arg-Glu-Asp (RED) at a surface antigenic loop of the viral capsid. The RED reverted to the...
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