Article
Viruses as quasispecies: biological implications.
Current topics in microbiology and immunology - 1 Jan 2006
Domingo E, Martin V, Perales C, Grande-Pérez A, García-Arriaza J, Arias A
Abstract excerpt
During viral infections, the complex and dynamic distributions of variants, termed viral quasispecies, play a key role in the adaptability of viruses to changing environments and the fate of the population as a whole. Mutant spectra are continuously and avoidably generated during RNA genome replication, and they are not just a by-product of error-prone replication, devoid of biological relevance. On the contrary,...
Topics
- Evolution, Molecular
- Genome, Viral
- Mutation
- RNA Viruses
- Viruses
