Article
Characterization of minority subpopulations in the mutant spectrum of HIV-1 quasispecies by successive specific amplifications.
Virus research - 1 Nov 2007
García-Arriaza Juan, Domingo Esteban, Briones Carlos
Abstract excerpt
RNA viruses do not replicate as defined genomic nucleotide sequences but rather as complex distributions of mutant genomes termed viral quasispecies. Quasispecies dynamics has a number of relevant biological consequences in ribo- and retroviruses, among these the possible presence of memory genomes as minority components of their mutant spectra. Minority memory genomes reflect those viral subpopulations that were...
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