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Article

Variation in the purinergic P2RX(7) receptor gene and schizophrenia.

Schizophrenia research - 1 Sept 2008

Hansen Thomas, Jakobsen Klaus D, Fenger Mogens, Nielsen Jimmi, Krane Karoline, Fink-Jensen Anders, Lublin Henrik, Ullum Henrik, Timm Sally, Wang August G, Jørgensen Niklas Rye, Werge Thomas

Abstract excerpt

INTRODUCTION: The purinergic receptor gene P2RX(7) is located in a major linkage hotspot for schizophrenia and bipolar disorders, 12q21-33. It has previously been associated with bipolar disorder but has never been analysed in relation to schizophrenia, although it is involved in several neuronal processes associated with schizophrenia. METHODS: Nine functionally characterised variants in P2RX(7) were genotyped...

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PMID: 18614336
DOI: 10.1016/j.schres.2008.05.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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