Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function.

Molecular genetics and genomics : MGG - 1 Sept 2008

Gustavsson Marie, Barmark Gunilla, Larsson Jimmy, Murén Eva, Ronne Hans

Abstract excerpt

We have screened a complete collection of yeast knockout mutants for sensitivity to monensin, an ionophore that interferes with intracellular transport. A total of 63 sensitive strains were found. Most of the strains were deleted for genes involved in post-Golgi traffic, with an emphasis on vacuolar biogenesis. A high correlation was thus seen with VPS and VAM genes, but there were also significant differences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cathepsin A
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomes

Share to Golgi Apparatus

Share to Phosphatidylinositols

Share to Sodium Chloride

Share to Vacuolar Proton-Translocating ATPases

Share to Vacuoles

Source

Identifiers

PMID: 18612650
DOI: 10.1007/s00438-008-0359-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional genomics of monensin sensitivity in yeast: implications for post-Golgi traffic and vacuolar H+-ATPase function.PMID 18612650Read ↗

Identification of yeast deletion strains that are hypersensitive to brefeldin A or monensin, two drugs that affect intracellular transport.Semantic proximity Read ↗

Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae.Semantic proximity Read ↗

Consequences of loss of Vph1 protein-containing vacuolar ATPases (V-ATPases) for overall cellular pH homeostasis.Semantic proximity Read ↗

A genomewide screen for tolerance to cationic drugs reveals genes important for potassium homeostasis in Saccharomyces cerevisiae.Semantic proximity Read ↗

A phenomics approach in yeast links proton and calcium pump function in the Golgi.Semantic proximity Read ↗

A genomic screen for yeast vacuolar membrane ATPase mutants.Semantic proximity Read ↗

The long physiological reach of the yeast vacuolar H+-ATPase.Semantic proximity Read ↗

Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.Semantic proximity Read ↗

A novel family of yeast chaperons involved in the distribution of V-ATPase and other membrane proteins.Semantic proximity Read ↗

A genome-wide immunodetection screen in S. cerevisiae uncovers novel genes involved in lysosomal vacuole function and morphology.Semantic proximity Read ↗

Vacuolar and plasma membrane proton pumps collaborate to achieve cytosolic pH homeostasis in yeast.Semantic proximity Read ↗

Characterization of yeast V-ATPase mutants lacking Vph1p or Stv1p and the effect on endocytosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.