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Article

Analysis of heterogeneity and epistasis in physiological mixed populations by combined structural equation modelling and latent class analysis.

BMC genetics - 8 Jul 2008

Fenger Mogens, Linneberg Allan, Werge Thomas, Jørgensen Torben

Abstract excerpt

BACKGROUND: Biological systems are interacting, molecular networks in which genetic variation contributes to phenotypic heterogeneity. This heterogeneity is traditionally modelled as a dichotomous trait (e.g. affected vs. non-affected). This is far too simplistic considering the complexity and genetic variations of such networks. METHODS: In this study on type 2 diabetes mellitus, heterogeneity was resolved in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18611252
DOI: 10.1186/1471-2156-9-43
PMCID: PMC2483291

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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