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Article

Enhanced detection of genetic association of hypertensive heart disease by analysis of latent phenotypes.

Genetic epidemiology - 1 Sept 2008

Gu C Charles, Flores Hubert R, de las Fuentes Lisa, Dávila-Román Victor G

Abstract excerpt

Hypertension and hypertensive heart disease (HHD) are inter-related phenotypes frequently observed with other comorbidities such as diabetes, obesity, and dyslipidemia, which probably reflect the complex gene-gene and/or gene-environment interactions resulting in HHD. The complexity of HHD led us to examine intermediate phenotypes (e.g., echocardiographically-derived measures) for simpler clues to the genetic...

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Identifiers

PMID: 18435473
DOI: 10.1002/gepi.20326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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