Fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips.

doi:10.1038/nature01672

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Article

Fission yeast mod5p regulates polarized growth through anchoring of tea1p at cell tips.

Nature - 5 Jun 2003

Snaith Hilary A, Sawin Kenneth E

Abstract excerpt

Microtubules have a central role in eukaryotic cell polarity, in part through interactions between microtubule end-binding proteins and the cell cortex. In the fission yeast Schizosaccharomyces pombe, microtubules and the polarity modulator tea1p maintain cylindrical cell shape and strictly antipodal cell growth. The tea1p protein is transported to cell tips by association with growing microtubule plus ends; once...

Topics

Cell Membrane
Cell Polarity
Gene Deletion
Microtubule-Associated Proteins
Microtubules
Phenotype
Protein Binding
Protein Transport
Schizosaccharomyces
Schizosaccharomyces pombe Proteins

Source

Open in PubMed

Identifiers

PMID: 12789340
DOI: 10.1038/nature01672

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