Article
A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery.
Molecular biology of the cell - 1 Nov 2003
Boldogh Istvan R, Nowakowski Dan W, Yang Hyeong-Cheol, Chung Haesung, Karmon Sharon, Royes Patrina, Pon Liza A
Abstract excerpt
Previous studies indicate that two proteins, Mmm1p and Mdm10p, are required to link mitochondria to the actin cytoskeleton of yeast and for actin-based control of mitochondrial movement, inheritance and morphology. Both proteins are integral mitochondrial outer membrane proteins. Mmm1p localizes to punctate structures in close proximity to mitochondrial DNA (mtDNA) nucleoids. We found that Mmm1p and Mdm10p exist...
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