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Article

Lysate-based pipeline to characterize microtubule-associated proteins uncovers unique microtubule behaviours.

Nature cell biology - 1 Feb 2022

Jijumon A S, Bodakuntla Satish, Genova Mariya, Bangera Mamata, Sackett Violet, Besse Laetitia, Maksut Fatlinda, Henriot Veronique, Magiera Maria M, Sirajuddin Minhajuddin, Janke Carsten

Abstract excerpt

The microtubule cytoskeleton forms complex macromolecular assemblies with a range of microtubule-associated proteins (MAPs) that have fundamental roles in cell architecture, division and motility. Determining how an individual MAP modulates microtubule behaviour is an important step in understanding the physiological roles of various microtubule assemblies. To characterize how MAPs control microtubule properties...

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PMID: 35102268
DOI: 10.1038/s41556-021-00825-4

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