Article
Analysis of BDNF Val66Met allele-specific mRNA levels in bipolar disorder.
Neuroscience letters - 22 Aug 2008
De Luca Vincenzo, Strauss John, Semeralul Mawahib, Huang Sheeda, Li Peter P, Warsh Jerry J, Kennedy James L, Wong Albert H C
Abstract excerpt
We have previously reported an association between the BDNF Val66Met polymorphism and bipolar disorder (BD). However, the possibility that genomic imprinting in BDNF gene affects risk for BD has not been investigated. To examine the possibility of genomic imprinting in the BDNF gene in BD, we analyzed the parent-of-origin effect (POE) and differential expression of the BDNF Val66Met alleles in BD. We performed a...
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