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Article

MultiRTA: a simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes.

BMC bioinformatics - 24 Sept 2010

Bordner Andrew J, Mittelmann Hans D

Abstract excerpt

BACKGROUND: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitopes has potential applications in vaccine design and in better understanding autoimmune diseases and allergies. However, comprehensive experimental determination of peptide-MHC binding affinities is infeasible due to MHC diversity and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

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Identifiers

PMID: 20868497
DOI: 10.1186/1471-2105-11-482
PMCID: PMC2957400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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