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Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate

1 Dec 2008

Abstract excerpt

BACKGROUND: Understanding the molecular control of cell lineages and fate determination in complex tissues is key to not only understanding the developmental biology and cellular homeostasis of such tissues but also for our understanding and interpretation of the molecular pathology of diseases such as cancer. The prerequisite for such an understanding is detailed knowledge of the cell types that make up such...

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PMID: 19063729
DOI: 10.1186/1471-2164-9-591

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