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Article

The endothelin-1 G5665T polymorphism impacts transplant-free survival for single ventricle patients.

The Journal of thoracic and cardiovascular surgery - 1 Jul 2008

Kirshbom Paul M, Mahle William T, Joyner Ronald W, Leong Traci, Wilson Malania, Kogon Brian E, Kanter Kirk R, Bouzyk Mark M

Abstract excerpt

BACKGROUND: Early survival for children with single-ventricle congenital heart disease has improved, but late attrition remains a serious problem. The endothelin-1 G5665T single nucleotide polymorphism has been linked to increased vascular reactivity and hypertension. The goal of this study was to determine whether this single nucleotide polymorphism alters transplant-free survival for children with...

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Source

Identifiers

PMID: 18603063
DOI: 10.1016/j.jtcvs.2008.02.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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