Article
Adrenergic receptor genotypes influence postoperative outcomes in infants in the Single-Ventricle Reconstruction Trial.
The Journal of thoracic and cardiovascular surgery - 1 Nov 2017
Ramroop Ronand, Manase George, Lu Danny, Manase Dorin, Chen Shan, Kim Richard, Lee Teresa, Mahle William T, McHugh Kimberly, Mitchell Mike, Tristani-Firouzi Martin, Wechsler Stephanie B, Wilder Nicole S, Zak Victor, Lafreniere-Roula Myriam, Newburger Jane W, Gaynor J William, Russell Mark W, Mital Seema
Abstract excerpt
OBJECTIVES: Adrenergic receptor (ADR) genotypes have been associated with adverse outcomes in heart failure. Our objective was to evaluate the association of ADR genotypes with post-Norwood outcomes in infants with hypoplastic left heart syndrome (HLHS). METHODS: Infants with HLHS participating in the Pediatric Heart Network Single-Ventricle Reconstruction Trial underwent genotyping for 4 single-nucleotide...
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