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Article

Genetic Polymorphisms in Endothelin-1 as Predictors for Long-Term Survival and the Cardiac Index in Patients Undergoing On-Pump Cardiac Surgery.

PloS one - 1 Jan 2015

Mansur Ashham, Steinau Maximilian, Popov Aron Frederik, Milenovic Sinisa, Bireta Christian, Weymann Alexander, Schotola Hanna, Wiese Christoph H, Beissbarth Tim, Tzvetkov Mladen, Hinz José

Abstract excerpt

Genetic variants within the endothelin-1 gene (EDN1) have been associated with several cardiovascular diseases and may act as genetic prognostic markers. Here, we explored the overall relevance of EDN1 polymorphisms for long-term survival in patients undergoing on-pump cardiac surgery. A prospectively collected cohort of 455 Caucasian patients who underwent cardiac surgery with cardiopulmonary bypass was followed...

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Identifiers

PMID: 26121692
DOI: 10.1371/journal.pone.0131155
PMCID: PMC4487899

Genes

EDN1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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