Article
Patient genotypes impact survival after surgery for isolated congenital heart disease.
The Annals of thoracic surgery - 1 Jul 2014
Kim Daniel Seung, Kim Jerry H, Burt Amber A, Crosslin David R, Burnham Nancy, McDonald-McGinn Donna M, Zackai Elaine H, Nicolson Susan C, Spray Thomas L, Stanaway Ian B, Nickerson Deborah A, Russell Mark W, Hakonarson Hakon, Gaynor J William, Jarvik Gail P
Abstract excerpt
BACKGROUND: Survival after cardiac surgery in infancy requires adaptive responses from oxidative stress management and vascular regulation pathways. We tested the hypothesis that genetic variation in these pathways influences postoperative survival in nonsyndromic congenital heart disease children. METHODS: This is an analysis of a cohort of nonsyndromic congenital heart disease patients who underwent cardiac...
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