Article
Renin-angiotensin-aldosterone system genotype and serum BNP in a contemporary cohort of adults late after Fontan palliation.
International journal of cardiology - 15 Oct 2015
Burchill Luke J, Redington Andrew N, Silversides Candice K, Ross Heather J, Jimenez-Juan Laura, Mital Seema, Oechslin Erwin N, Dragulescu Andreea, Slorach Cameron, Mertens Luc, Wald Rachel M
Abstract excerpt
BACKGROUND: Adults with single ventricle physiology palliated with a Fontan circulation experience high mortality due to circulatory failure. Renin-angiotensin-aldosterone system (RAAS) genotype contributes to adverse cardiovascular outcomes in acquired heart failure. This study evaluated associations between RAAS genotype, ventricular mass and function in a contemporary cohort of adults with a Fontan...
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