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EGFR and MMP-9 are associated with neointimal hyperplasia in systemic-to-pulmonary shunts in children with complex cyanotic heart disease

2022-09-09

Abstract excerpt

INTRODUCTION: Systemic-to-pulmonary (SP) shunt malfunction contributes to morbidity in infants with single ventricle physiology after palliative procedure. Neointimal hyperplasia might play a role in the pathogenesis, increasing risk for shunt obstruction. Epidermal growth factor receptor (EGFR) and matrix-metalloproteinase 9 (MMP-9) are described as contributors for neointimal formation in other diseases. Aim of...

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Literature Corpus work
cd4b66c6-1569-5482-aa8d-10ebbe66c782
DOI
10.21203/rs.3.rs-2015333/v1
Open publication

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EGFR and MMP-9 are associated with neointimal hyperplasia in systemic-to-pulmonary shunts in children with complex cyanotic heart diseaseDOI 10.21203/rs.3.rs-2015333/v1
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