Article
β1-receptor polymorphisms and junctional ectopic tachycardia in children after cardiac surgery.
Clinical and translational science - 1 Mar 2022
Dumeny Leanne, Chantra Marut, Langaee Taimour, Duong Benjamin Q, Zambrano Daniel H, Han Frank, Lopez-Colon Dalia, Humma James F, Dacosta Jonathan, Lovato Tommie, Mei Connie, Duarte Julio D, Johnson Julie A, Peek Giles J, Jacobs Jeffrey P, Bleiweis Mark S, Cavallari Larisa H
Abstract excerpt
Junctional ectopic tachycardia (JET) is a potentially life-threatening postoperative arrhythmia in children with specific congenital heart defects and can contribute significantly to postoperative morbidity for at-risk populations. In adults, β1-adrenergic receptor (ADRB1) and β2-adrenergic receptor (ADRB2) genotypes have been associated with increased risk for arrhythmias. However, their association with...
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