Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Age-dependent association of human mannose-binding lectin mutations with susceptibility to invasive meningococcal disease in childhood.

The Pediatric infectious disease journal - 1 Mar 2007

Faber Joerg, Schuessler Therese, Finn Adam, Murdoch Craig, Zenz Werner, Habermehl Pirmin, Meyer Claudius U, Zabel Bernhard U, Schmitt Heinz, Zepp Fred, Knuf Markus

Abstract excerpt

BACKGROUND: Mannose-binding lectin (MBL) is an important factor of the innate immune system, and MBL-initiated complement activation is an important early defense mechanism against various bacterial infections, including invasive meningococcal disease. METHODS: In a pediatric cohort (ages 2-215 m...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aging
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Infant

Share to Mannose-Binding Lectin

Share to Meningococcal Infections

Share to Prevalence

Source

Identifiers

PMID: 17484222
DOI: 10.1097/01.inf.0000256751.76218.7c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17484222-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Age-dependent association of human mannose-binding lectin mutations with susceptibility to invasive meningococcal disease in childhood.PMID 17484222Read ↗

High prevalence of genetically-determined mannose binding lectin deficiency in young children with invasive pneumococcal disease.Semantic proximity Read ↗

An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1-related disease in children.Semantic proximity Read ↗

Mannose-binding lectin genotype is associated with respiratory disease in young children: A multicenter cohort study.Semantic proximity Read ↗

Association between mannose binding lectin gene polymorphisms and clinical severity of COVID-19 in children.Semantic proximity Read ↗

Association of variants of the gene for mannose-binding lectin with susceptibility to meningococcal disease. Meningococcal Research Group.Semantic proximity Read ↗

Serum mannose-binding lectin levels and mbl2 gene polymorphisms in different age and gender groups of southern Chinese adults.Semantic proximity Read ↗

Mannose-binding lectin genotype influences frequency and duration of infectious complications in children with malignancy.Semantic proximity Read ↗

Mannose-binding lectin-deficient genotypes as a risk factor of pneumococcal meningitis in infants.Semantic proximity Read ↗

MBL2 deficiency is associated with higher genomic bacterial loads during meningococcemia in young children.Semantic proximity Read ↗

Deficiency of mannose-binding lectin and burden of infection in children with malignancy: a prospective study.Semantic proximity Read ↗

Mannose-binding lectin in susceptibility and progression of HIV-1 infection in children.Semantic proximity Read ↗

Genetic susceptibility to invasive meningococcal disease: MBL2 structural polymorphisms revisited in a large case-control study and a systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.