Article
Paraoxonase 1 activities and genetic variation in childhood obesity.
The British journal of nutrition - 14 Nov 2013
Rupérez A I, López-Guarnido O, Gil F, Olza J, Gil-Campos M, Leis R, Tojo R, Cañete R, Gil A, Aguilera C M
Abstract excerpt
Changes in paraoxonase 1 (PON1) activities have been observed in a variety of diseases involving oxidative stress, such as CVD. However, its role in obesity has not been fully established. In the present study, we aimed (1) to genotype sixteen PON1 SNP, (2) to measure serum PON1 activities and (3) to correlate these findings with the incidence of childhood obesity and related traits. We conducted a case-control...
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