Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APOBEC3G Incorporation into Human Immunodeficiency Virus Type 1 Particles

12 Oct 2004

Abstract excerpt

APOBEC3G is promiscuous with respect to its antiretroviral effect, requiring that it be packaged into diverse retrovirus particles. Here, we show that most virally encoded human immunodeficiency virus type 1 particle components are dispensable for APOPEC3G incorporation. However, replacement of the nucleocapsid (NC) Gag domain with a leucine zipper abolished APOBEC3G incorporation. Moreover, coprecipitation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV Research and Treatment
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15479846
DOI: 10.1128/jvi.78.21.12058-12061.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APOBEC3G Incorporation into Human Immunodeficiency Virus Type 1 ParticlesPMID 15479846Read ↗

Amino-Terminal Region of the Human Immunodeficiency Virus Type 1 Nucleocapsid Is Required for Human APOBEC3G PackagingSemantic proximity Read ↗

Specific packaging of APOBEC3G into HIV-1 virions is mediated by the nucleocapsid domain of the gag polyprotein precursorSemantic proximity Read ↗

Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1Semantic proximity Read ↗

Viral RNA Is Required for the Association of APOBEC3G with Human Immunodeficiency Virus Type 1 Nucleoprotein ComplexesSemantic proximity Read ↗

7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3G.Semantic proximity Read ↗

Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging.Semantic proximity Read ↗

Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerizationSemantic proximity Read ↗

How HIV-1 Gag Manipulates Its Host Cell Proteins: A Focus on Interactors of the Nucleocapsid DomainSemantic proximity Read ↗

Functional Analysis and Structural Modeling of Human APOBEC3G Reveal the Role of Evolutionarily Conserved Elements in the Inhibition of Human Immunodeficiency Virus Type 1 Infection and <i>Alu</i> TranspositionSemantic proximity Read ↗

Molecular mechanisms of simian immunodeficiency virus SIV(agm) RNA encapsidation.Semantic proximity Read ↗

GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity.Semantic proximity Read ↗

Identification of Amino Acid Residues in APOBEC3G Required for Regulation by Human Immunodeficiency Virus Type 1 Vif and Virion EncapsidationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.