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Article

Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging.

Journal of molecular biology - 25 Jan 2008

Wang Tao, Tian Chunjuan, Zhang Wenyan, Sarkis Phuong Thi Nguyen, Yu Xiao-Fang

Abstract excerpt

Human cytidine deaminase apolipoprotein B mRNA-editing catalytic polypeptide-like 3F (APOBEC3F, or A3F), like APOBEC3G, has broad antiviral activity against diverse retroelements, including Vif-deficient human immunodeficiency virus (HIV)-1. Its antiviral functions are known to rely on its virion encapsidation and be suppressed by HIV-1 Vif, which recruits Cullin5-based E3 ubiquitin ligases. However, the factors...

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Share to Cytosine Deaminase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

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Source

Identifiers

PMID: 18067920
DOI: 10.1016/j.jmb.2007.11.017

Genes

SRP19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction with 7SL RNA but not with HIV-1 genomic RNA or P bodies is required for APOBEC3F virion packaging.PMID 18067920Read ↗

7SL RNA mediates virion packaging of the antiviral cytidine deaminase APOBEC3G.Semantic proximity Read ↗

Virion packaging determinants and reverse transcription of SRP RNA in HIV-1 particlesSemantic proximity Read ↗

Amino-Terminal Region of the Human Immunodeficiency Virus Type 1 Nucleocapsid Is Required for Human APOBEC3G PackagingSemantic proximity Read ↗

Promiscuous RNA Binding Ensures Effective Encapsidation of APOBEC3 Proteins by HIV-1Semantic proximity Read ↗

Association of Potent Human Antiviral Cytidine Deaminases with 7SL RNA and Viral RNP in HIV-1 VirionsSemantic proximity Read ↗

Characterization of APOBEC3G binding to 7SL RNA.Semantic proximity Read ↗

GANP interacts with APOBEC3G and facilitates its encapsidation into the virions to reduce HIV-1 infectivity.Semantic proximity Read ↗

Role of HIV-1 RNA and protein determinants for the selective packaging of spliced and unspliced viral RNA and host U6 and 7SL RNA in virus particles.Semantic proximity Read ↗

Viral RNA Is Required for the Association of APOBEC3G with Human Immunodeficiency Virus Type 1 Nucleoprotein ComplexesSemantic proximity Read ↗

APOBEC3G Complexes Decrease Human Immunodeficiency Virus Type 1 ProductionSemantic proximity Read ↗

Human Immunodeficiency Virus Type 1 Preferentially Encapsidates Genomic RNAs That Encode Pr55Gag: Functional Linkage between Translation and RNA PackagingSemantic proximity Read ↗

cis-Acting determinants of 7SL RNA packaging by HIV-1.Semantic proximity Read ↗

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