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Article

Evolution and polymorphism of poliovirus genomes.

Biologicals : journal of the International Association of Biological Standardization - 1 Dec 1993

Crainic R, Kew O

Abstract excerpt

The three poliovirus serotypes are very stable. Breakthrough of the serotype barrier has never been observed in the natural evolution of poliovirus. This serotype stability contrasts with the high level of genomic and phenotypic variability that occurs within the bounds of serotype. The efficient control of poliomyelitis by immunization is based upon type-specific immunity and serotype stability. The development...

Topics

Animals
Antigens, Viral
Biological Evolution
Capsid
Genetic Variation
Genome, Viral
Humans
Mutation
Poliomyelitis
Poliovirus
Poliovirus Vaccine, Oral
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Population Surveillance

RNA, Viral

Virulence

Source

Identifiers

PMID: 8024754
DOI: 10.1006/biol.1993.1099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8024754-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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