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Article

Do glutathione-S-transferase polymorphisms influence response to intravenous cyclophosphamide therapy in idiopathic nephrotic syndrome?

Pediatric nephrology (Berlin, Germany) - 1 Nov 2008

Sharda Sheetal V, Gulati Sanjeev, Tripathi Gaurav, Jafar Tabrez, Kumar Alok, Sharma Raj Kumar, Agrawal Suraksha

Abstract excerpt

The response to cyclophosphamide (CP) is variable and difficult to predict in children with idiopathic nephrotic syndrome (INS). The polymorphic expression of glutathione-S-transferase (GST) may affect the remission rate after CP therapy. In this study, we evaluated the correlation of GST polymorphism and response to CP in INS. We studied GST polymorphism in 74 children with steroid-sensitive (44) and...

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Share to Cyclophosphamide
Share to Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Injections, Intravenous

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Source

Identifiers

PMID: 18594869
DOI: 10.1007/s00467-008-0883-1

Genes

GSTM1
GSTP1
GSTT1
INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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