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Article

Genetic variation in the TNF receptor-associated factor 6 gene is associated with susceptibility to sepsis-induced acute lung injury.

Journal of translational medicine - 17 Aug 2012

Song Zhenju, Yao Chenling, Yin Jun, Tong Chaoyang, Zhu Duming, Sun Zhan, Jiang Jinjun, Shao Mian, Zhang Yaping, Deng Zhi, Tao Zhengang, Sun Si, Bai Chunxue

Abstract excerpt

BACKGROUND: Recent studies showed that overwhelming inflammatory response mediated by the toll-like receptor (TLR)-related pathway was important in the development of acute lung injury (ALI). The aim of this study was to determine whether common genetic variation in four genes of the TLR signalin...

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Source

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Identifiers

PMID: 22901274
DOI: 10.1186/1479-5876-10-166
PMCID: PMC3478205

Genes

TRAF6
TNF
IRAK1
IRAK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22901274-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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