Article
A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury.
Critical care (London, England) - 1 Jan 2008
Flores Carlos, Pino-Yanes Maria del Mar, Villar Jesús
Abstract excerpt
INTRODUCTION: Clinical observations and animal models provide evidence that the development of acute lung injury (ALI), a phenomenon of acute diffuse lung inflammation in critically ill patients, is influenced by genetic factors. Association studies are the main tool for exploring common genetic variations underlying ALI susceptibility and/or outcome. We aimed to assess the quality of positive genetic association...
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