Article
The association of interleukin 6 haplotype clades with mortality in critically ill adults.
Archives of internal medicine - 10 Jan 2005
Sutherland Ainsley M, Walley Keith R, Manocha Sanjay, Russell James A
Abstract excerpt
BACKGROUND: Interleukin 6 (IL-6) is a key proinflammatory cytokine in the systemic inflammatory response syndrome (SIRS). A G-->C polymorphism at position -174 of the IL-6 gene is associated with an adverse outcome in a number of inflammatory diseases, although its association with sepsis as an outcome remains unclear. We tested the hypothesis that specific haplotype clades of IL-6 may be associated with an...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.