Article
Genetic variations in soluble epoxide hydrolase and graft function in kidney transplantation.
Transplantation proceedings - 1 Jun 2008
Lee S H, Lee J, Cha R, Park M H, Ha J W, Kim S, Kim Y S
Abstract excerpt
BACKGROUND: Epoxyeicosatrienoic acids (EETs) are endothelium-derived hyperpolarizing factors that contribute renal protective actions. The aim of this study was to identify the association between genetic variations in soluble epoxide hydrolase (EPHX2, EET-metabolizing enzyme) and kidney allograft dysfunction. MATERIALS AND METHODS: Data from 204 kidney transplant donor-recipient pairs were examined for...
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