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Article

Polymorphisms in CYP-mediated arachidonic acid routes affect the outcome of renal transplantation.

European journal of clinical investigation - 1 Oct 2015

Gervasini Guillermo, García-Cerrada Montserrat, Vergara Esther, García-Pino Guadalupe, Alvarado Raul, Fernández-Cavada Maria Jesús, Barroso Sergio, Doblaré Emilio, Cubero Juan José

Abstract excerpt

BACKGROUND: Arachidonic acid (AA) is metabolized by cytochrome P450 (CYP) enzymes to vasoactive metabolites (mainly epoxyeicosatrienoic acids) which are known to play a protective role against damaging processes that may occur after re-oxygenation of the graft. We aimed to investigate whether the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26214067
DOI: 10.1111/eci.12507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26214067-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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