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Article

Polymorphisms in genes involved in vasoactive eicosanoid synthesis affect cardiovascular risk in renal transplant recipients.

Current medical research and opinion - 1 Feb 2018

Gervasini Guillermo, Luna Enrique, Garcia-Pino Guadalupe, Azevedo Lilia, Mota-Zamorano Sonia, José Cubero Juan

Abstract excerpt

OBJECTIVE: Arachidonic acid metabolism by cytochrome P450 (CYP) epoxygenases leads to epoxyeicosatrienoic acids (EETs), which are eicosanoids with vasodilator and anti-inflammatory properties. We aim to determine whether genetic variability in these routes may contribute to cardiovascular (CV) risk in renal transplant recipients. METHODS: In a cohort of 355 patients, we determined the presence of two...

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Source

Identifiers

PMID: 29022765
DOI: 10.1080/03007995.2017.1391757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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