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Article

The kisspeptin (KiSS-1)/GPR54 system in cancer biology.

Cancer treatment reviews - 1 Dec 2008

Makri Angeliki, Pissimissis Nikolaos, Lembessis Peter, Polychronakos Constantine, Koutsilieris Michael

Abstract excerpt

Kisspeptin (KiSS-1) gene, initially described as a melanoma metastasis suppressor gene, encodes a number of peptides (kp-54, kp-14, kp-13, kp-10), which are endogenous ligands to a G protein-coupled receptor, referred as hOT7T175 or AXOR12 or GPR54. So far intensive investigation has provided substantiate evidence supporting the role of KiSS-1/GPR54 system in cancer biology as well as in the regulation of the...

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Identifiers

PMID: 18583061
DOI: 10.1016/j.ctrv.2008.05.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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