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Article

The neuroendocrine physiology of kisspeptin in the human.

Reviews in endocrine & metabolic disorders - 1 Mar 2007

Dhillo Waljit S, Murphy Kevin G, Bloom Stephen R

Abstract excerpt

Kisspeptin is a 54-amino acid peptide, encoded by the KiSS-1 gene, which activates the G protein-coupled receptor GPR54. Recent evidence suggests the kisspeptin/GPR54 system is a key regulator of reproduction. GPR54-deficient mice have abnormal sexual development. Central or peripheral administration of kisspeptin stimulates the hypothalamic-pituitary-gonadal (HPG) axis in animal models. This review discusses the...

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Identifiers

PMID: 17323132
DOI: 10.1007/s11154-007-9029-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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