Article
A role for kisspeptins in pregnancy: facts and speculations.
Reproduction (Cambridge, England) - 1 Jul 2009
Reynolds Rebecca M, Logie James J, Roseweir Antonia K, McKnight Angus J, Millar Robert P
Abstract excerpt
Kisspeptin is a neuropeptide that was originally discovered in 1996 from a metastasis tumour suppressor gene, KISS1 and was appropriately named metastin. More recently, the discovery of inactivating mutations in the receptor for kisspeptin, a G protein-coupled receptor, GPR54 (KISS1R), have been shown to result in a failure to progress through puberty in man. These findings have led to the kisspeptin/KISS1R...
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