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Article

KISS1 in metastatic cancer research and treatment: potential and paradoxes.

Cancer metastasis reviews - 1 Sept 2020

Ly Thuc, Harihar Sitaram, Welch Danny R

Abstract excerpt

The significance of KISS1 goes beyond its original discovery as a metastasis suppressor. Its function as a neuropeptide involved in diverse physiologic processes is more well studied. Enthusiasm regarding KISS1 has cumulated in clinical trials in multiple fields related to reproduction and metabolism. But its cancer therapeutic space is unsettled. This review focuses on collating data from cancer and non-cancer...

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Topics

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Share to Epigenesis, Genetic
Share to Hypothalamic control of reproductive hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kisspeptins

Share to Neoplasm Metastasis

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Share to Neuropeptides and Animal Physiology

Share to Polymorphism, Single Nucleotide

Share to Receptors, Kisspeptin-1

Source

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Identifiers

PMID: 32152912
DOI: 10.1007/s10555-020-09868-9
PMCID: PMC7483209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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