Article
Why kisspeptin is such important for reproduction?
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jan 2011
Meczekalski Blazej, Podfigurna-Stopa Agnieszka, Genazzani Andrea Riccardo
Abstract excerpt
Recently discovered neuropeptide called kisspeptin is thought to be an essential gatekeeper in control of reproduction. Kisspeptin, the product of KiSS-1 gene and its G protein-coupled receptor GPR54 play a master role in the puberty period and fertility. This 54 amino acid peptide known also as metastatin, because of its metastasis suppression ability is also implicated in tumour biology. Kisspeptin/GPR54 system...
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