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Article

Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye.

Developmental biology - 1 Aug 2008

Dakubo Gabriel D, Mazerolle Chantal, Furimsky Marosh, Yu Chuan, St-Jacques Benoit, McMahon Andrew P, Wallace Valerie A

Abstract excerpt

The development of extraocular orbital structures, in particular the choroid and sclera, is regulated by a complex series of interactions between neuroectoderm, neural crest and mesoderm derivatives, although in many instances the signals that mediate these interactions are not known. In this study we have investigated the function of Indian hedgehog (Ihh) in the developing mammalian eye. We show that Ihh is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18582859
DOI: 10.1016/j.ydbio.2008.05.528

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye.PMID 18582859Read ↗

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