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Article

Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease.

American journal of nephrology - 1 Jan 2008

Hicks Pamela J, Staten Jennifer L, Palmer Nicholette D, Langefeld Carl D, Ziegler Julie T, Keene Keith L, Sale Michele M, Bowden Donald W, Freedman Barry I

Abstract excerpt

BACKGROUND: Genome scans in African-Americans with end-stage renal disease (ESRD) identified linkage on chromosome 13q33 in the region containing the ephrin-B2 ligand (EFNB2) genes. Interactions between the ephrin-B2 receptor and ephrin-B2 ligand play essential roles in renal angiogenesis, blood vessel maturation, and kidney disease. METHODS: The EFNB2 gene was evaluated as a positional candidate for non-diabetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18580054
DOI: 10.1159/000141934
PMCID: PMC2786015

Genes

EFNB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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