Article
Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.
PloS one - 1 Jan 2014
Palmer Nicholette D, Ng Maggie C Y, Hicks Pamela J, Mudgal Poorva, Langefeld Carl D, Freedman Barry I, Bowden Donald W
Abstract excerpt
Type 2 diabetes (T2D)-associated end-stage kidney disease (ESKD) is a complex disorder resulting from the combined influence of genetic and environmental factors. This study contains a comprehensive genetic analysis of putative nephropathy loci in 965 African American (AA) cases with T2D-ESKD and 1029 AA population-based controls extending prior findings. Analysis was based on 4,341 directly genotyped and imputed...
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