Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of podocin (NPHS2) gene mutations in African Americans with nondiabetic end-stage renal disease.

Kidney international - 1 Jul 2005

Dusel Judith A Engeler, Burdon Kathryn P, Hicks Pamela J, Hawkins Gregory A, Bowden Donald W, Freedman Barry I

Abstract excerpt

BACKGROUND: Podocin, encoded by NPHS2 and mapped to 1q25.2, is an integral membrane protein exclusively expressed in glomerular podocytes. Mutations in the NPHS2 gene cause autosomal-recessive nephrotic syndrome and have been associated with proteinuria in several populations. Evidence for linkage of end-stage renal disease (ESRD) to chromosome 1q25-31 in the region of NPHS2 has been identified in a genome-wide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Gene Frequency

Share to Haplotypes

Share to Intracellular Signaling Peptides and Proteins

Share to Kidney Failure, Chronic

Share to Membrane Proteins

Source

Identifiers

PMID: 15954915
DOI: 10.1111/j.1523-1755.2005.00400.x

Genes

NPHS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of podocin (NPHS2) gene mutations in African Americans with nondiabetic end-stage renal disease.PMID 15954915Read ↗

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome.Semantic proximity Read ↗

Coding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans.Semantic proximity Read ↗

NPHS2 variation in sporadic focal segmental glomerulosclerosis.Semantic proximity Read ↗

Rare functional variants of podocin (NPHS2) promoter in patients with nephrotic syndrome.Semantic proximity Read ↗

Novel NPHS2 variant in patients with familial steroid-resistant nephrotic syndrome with early onset, slow progression and dominant inheritance pattern.Semantic proximity Read ↗

NPHS2 variation in focal and segmental glomerulosclerosis.Semantic proximity Read ↗

Genetic effect of the NPHS2 gene variants on proteinuria in minimal change disease and immunoglobulin A nephropathy.Semantic proximity Read ↗

Association analysis of the ephrin-B2 gene in African-Americans with end-stage renal disease.Semantic proximity Read ↗

NPHS2 (podicin) mutations in Turkish children with idiopathic nephrotic syndrome.Semantic proximity Read ↗

NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated alleleSemantic proximity Read ↗

NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele.Semantic proximity Read ↗

NPHS2 (Podocin) mutations in nephrotic syndrome. Clinical spectrum and fine mechanisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.